Research Article
Improved Outcome of Severe Acute Pancreatitis in the Intensive Care Unit
Table 1
Baseline characteristics and outcomes.
| Parameter | Prevalence () |
| Male gender (%) | 31 (62%) | Mean age (SD; range) | 51.7 (14.8; 16–85) | Past Medical History | | Pancreatitis | 40% | Diabetes mellitus | 24% | Gallstone disease | 16% | Liver cirrhosis | 8% | Chronic kidney disease | 8% | Transplantation | 4% | Aetiology of severe pancreatitis | | Alcohol | 40% | Gallstone disease | 30% | Drug induced | 6% | Hypocalcaemia | 4% | Post ERCP | 2% | Hypertriglyceridemia | 2% | Idiopathic | 16% | Transfer from other hospital | 48% | Severity of illness on admission to ICU | | APACHE II score, median (IQR) | 17 (12–19) | SOFA, median (IQR) | 5 (3–8) | POP, median (IQR) | 8 (5–12) | CTSI, median (IQR) | 4 (2–7.5) | Associated organ failure | | AKI | 54% | ALI | 56% | IAH | 20% | Need for respiratory support | 78% | Need for RRT | 44% | Treatment with vasoactive drugs | 62% | Nutrition | | TPN | 20% | Enteral nutrition only | 80% | Interventional treatment | | Drain insertion | 24% | Surgical intervention | 26% | Embolisation | 7.5% | Outcome | | ICU mortality | 16% | Hospital mortality | 20% | LOS in ICU, median (IQR) | 13.5 (6–30) | LOS in Hospital, median (IQR) | 30 (16–70) | Diabetes mellitus in hospital survivors | 11 of 40 survivors | End stage renal failure in hospital survivors | 2 of 40 survivors |
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ICU: intensive care unit; ERCP: Endoscopic Retrograde Cholangiopancreatography; SD: standard deviation; IQR: interquartile range; APACHE: Acute Physiology and Chronic Health Evaluation; SOFA: sequential organ failure assessment; POP: pancreatitis outcome prediction; CTSI: Computed Tomography Severity Index; AKI: acute kidney injury; ALI: acute lung injury; IAH: intraabdominal hypertension; RRT: renal replacement therapy; TPN: total parenteral nutrition; LOS: length of stay.
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