Research Article
Etiology and Outcomes of ARDS in a Rural-Urban Fringe Hospital of South India
Table 3
Univariate analysis of risk factors for mortality.
| Variable | Number | Relative risk | CI | Significance |
| Demographics | | | | | Age > 50 years | 8/18 | 1.99 | 1.05–3.75 | 0.04* | Male sex | 12/32 | 1.08 | 0.55–2.13 | 0.50 | Illness duration < 1 week | 20/54 | 1.296 | 0.38–4.39 | 0.66 | Risk factors | | | | | Smoking | 8/16 | 1.60 | 0.83–3.09 | 0.17 | Alcohol | 7/14 | 1.56 | 0.82–3.06 | 0.21 | Smoking + alcohol | 7/12 | 1.90 | 1.00–3.60 | 0.07* | Comorbidities | 14/26 | 2.35 | 1.16–4.76 | 0.013* | Infection | 17/46 | 1.10 | 0.49–2.49 | 0.52 | Prior hospitalization | 5/7 | 2.26 | 1.23–4.18 | 0.038* | Clinical signs | | | | | Temperature > 100 F | 10/21 | 1.58 | 0.82–3.04 | 0.14 | Heart rate > 100 | 17/42 | 1.53 | 0.66–3.55 | 0.20 | Investigations | | | | | pH < 7.40 | 14/37 | 1.13 | 0.56–2.28 | 0.46 | TLC > 11 (×103/L) | 17/33 | 2.88 | 1.22–6.88 | 0.006* | Thrombocytopenia < 150 (×103/L) | 9/25 | 0.99 | 0.50–1.96 | 0.99 | Serum albumin < 3 g/dL | 13/35 | 1.07 | 0.54–2.12 | 0.83 | Nontropical infection | 32/46 | 3.28 | 0.86–12.47 | 0.04* | Organ dysfunction | | | | | AKI | 14/23 | 2.89 | 1.43–5.80 | 0.002* | Altered sensorium | 20/29 | 11.03 | 2.82–43.16 | <0.001* | Direct lung injury | 15/45 | 0.76 | 0.38–1.52 | 0.32 | ARDS | 38/61 | 1.92 | 1.34–2.75 | 0.001* | SGOT > 3 times elevation | 19/50 | 1.39 | 0.49–3.89 | 0.38 | SGPT > 3 times elevation | 20/54 | 1.29 | 0.38–4.39 | 0.50 | APACHE II score > 20 | 14/61 | 5.36 | 2.81–10.22 | <0.001* | Hospital course | | | | | ARDS after admission | 10/15 | 2.55 | 1.39–4.67 | 0.004* | Ventilation > 7 days | 11/17 | 2.58 | 1.39–4.81 | 0.005* | Inotrope use | 20/29 | 11.03 | 2.81–43.16 | <0.001* | CPR | 18/19 | 17.19 | 2.54–116.11 | <0.001* |
|
|
TLC: total leukocyte count; AKI: acute kidney injury; ARDS: acute respiratory distress syndrome; SOFA: sequential organ failure assessment score; APACHE: acute physiology and chronic health evaluation; SGOT: serum glutamic oxaloacetic transaminase; SGPT: serum glutamic-pyruvic transaminase; CPR: cardiopulmonary resuscitation. *indicates significant value <0.05
|