An Observational Study on Early Empiric versus Culture-Directed Antifungal Therapy in Critically Ill with Intra-Abdominal Sepsis

Table 4

Primary and secondary study outcomes.

	Empiric 𝑛=30 (%)	Culture-directed 𝑛=18 (%)	𝑃 value	Odds ratio (95% C.I.)
30-day overall mortality, 𝑛 (%)	6 (20)	9 (50)	0.030	0.25 (0.069, 0.905)
30-day fungal-related mortality, 𝑛 (%)	2 (7)	6 (33)	0.040	0.143 (0.025, 0.812)
Subjects with overall clinical improvement, 𝑛 (%)	20 (67)	9 (50)	0.253	2.00 (0.605, 6.612)
Median length of hospital stay (range)	41.00 (5–161)	47.50 (7–125)	0.906	—
Median length of SICU stay (range)	9 (0–53)	10 (0–51)	0.925	—