An Observational Study on Early Empiric versus Culture-Directed Antifungal Therapy in Critically Ill with Intra-Abdominal Sepsis

Table 5

Time to improvement from sepsis (in days).

	Median time to improvement (range)
	Overall clinical	Gut recovery	Drains removal	Normalization of leukocytes
Empiric	13 (4–48)	9 (0–48)	12.50 (3–38)	10 (2–48)
Culture-directed	35 (18–75)	18 (10–49)	31.50 (4–68)	26.50 (11–62)
𝑃 value	0.007	0.017	0.016	0.005