Procalcitonin Clearance for Early Prediction of Survival in Critically Ill Patients with Severe Sepsis
Table 1
Baseline demographics, clinical characteristics, and outcomes between patients with SIRS and sepsis.
Variables
All patients
Noninfectious SIRS
Sepsis
Age (years)
44 ± 16
41 ± 17
45 ± 16
0.26
Gender (male)
66 (69.5)
19 (67.9)
47 (70.1)
0.83
Weight (kg)
67 ± 16
69 ± 22
66 ± 13
0.45
Height (cm)
159 ± 18
155 ± 31
161 ± 8
0.14
Baseline SAPS II Score
39 ± 16
33 ± 13
41 ± 16
0.02
Baseline SOFA Score
7.2 ± 4.3
5.2 ± 2.6
8.0 ± 4.7
0.003
Primary admission diagnoses
0.001
Cardiovascular
6 (6.3)
2 (7.1)
4 (6.0)
Endocrine/metabolic
3 (28.6)
0 (0)
3 (4.5)
Gastrointestinal/hepatobiliary/pancreas
7 (7.4)
1 (3.6)
6 (9.0)
Infective
18 (18.9)
0 (0)
18 (26.9)
Renal
4 (4.2)
2 (7.1)
2 (3.0)
Neurological
12 (12.6)
3 (10.7)
9 (13.4)
Respiratory
20 (21.1)
6 (21.4)
14 (20.9)
Trauma
15 (15.8)
11 (39.3)
4 (6.0)
Postoperative surgical
4 (4.2)
3 (10.7)
1 (1.5)
Connective tissue/autoimmune
2 (2.1)
0 (0)
2 (3.0)
Maternity/gynaecological
3 (3.2)
0 (0)
3 (4.5)
Drug overdose/poisoning
1 (1.1)
0 (0)
1 (1.5)
Renal replacement therapy (RRT)
28 (29.5)
4 (14.3)
24 (35.8)
0.04
Hospital mortality
30 (31.6)
3 (10.7)
27 (40.3)
0.008
Mechanical ventilation (MV)
87 (91.6)
25 (89.3)
62 (92.5)
0.60
Length of MV (days)
4.8 (1.8–9.9)
4.7 (1.0–9.5)
4.9 (2.1–13.0)
0.41
Length of ICU stay (days)
7.0 (2.9–14.6)
6.8 (2.7–10.3)
7.0 (3.2–15.8)
0.46
Length of hospital stay (days)
12.3 (6.6–18.2)
12.4 (6.4–17.4)
12.3 (6.6–19.2)
0.73
Data are expressed as mean ± SD, (%), or median (lower quartile–upper quartile). SAPS II Score: Simplified Acute Physiological II Score. SOFA Score: Sequential Organ Failure Assessment Score. SIRS: systemic inflammatory response syndrome.