Clinical Study

Procalcitonin Clearance for Early Prediction of Survival in Critically Ill Patients with Severe Sepsis

Table 1

Baseline demographics, clinical characteristics, and outcomes between patients with SIRS and sepsis.

VariablesAll patients
Noninfectious SIRS
Sepsis

Age (years)44 ± 1641 ± 1745 ± 160.26
Gender (male)66 (69.5)19 (67.9)47 (70.1)0.83
Weight (kg)67 ± 1669 ± 2266 ± 130.45
Height (cm)159 ± 18155 ± 31161 ± 80.14
Baseline SAPS II Score39 ± 1633 ± 1341 ± 160.02
Baseline SOFA Score7.2 ± 4.35.2 ± 2.68.0 ± 4.70.003
Primary admission diagnoses0.001
 Cardiovascular6 (6.3)2 (7.1)4 (6.0)
 Endocrine/metabolic3 (28.6)0 (0)3 (4.5)
 Gastrointestinal/hepatobiliary/pancreas7 (7.4)1 (3.6)6 (9.0)
 Infective18 (18.9)0 (0)18 (26.9)
 Renal4 (4.2)2 (7.1)2 (3.0)
 Neurological12 (12.6)3 (10.7)9 (13.4)
 Respiratory20 (21.1)6 (21.4)14 (20.9)
 Trauma15 (15.8)11 (39.3)4 (6.0)
 Postoperative surgical4 (4.2)3 (10.7)1 (1.5)
 Connective tissue/autoimmune2 (2.1)0 (0)2 (3.0)
 Maternity/gynaecological3 (3.2)0 (0)3 (4.5)
 Drug overdose/poisoning1 (1.1)0 (0)1 (1.5)
Renal replacement therapy (RRT)28 (29.5)4 (14.3)24 (35.8)0.04
Hospital mortality30 (31.6)3 (10.7)27 (40.3)0.008
Mechanical ventilation (MV)87 (91.6)25 (89.3)62 (92.5)0.60
Length of MV (days)4.8 (1.8–9.9)4.7 (1.0–9.5)4.9 (2.1–13.0)0.41
Length of ICU stay (days)7.0 (2.9–14.6)6.8 (2.7–10.3)7.0 (3.2–15.8)0.46
Length of hospital stay (days)12.3 (6.6–18.2)12.4 (6.4–17.4)12.3 (6.6–19.2)0.73

Data are expressed as mean ± SD, (%), or median (lower quartile–upper quartile).
SAPS II Score: Simplified Acute Physiological II Score. SOFA Score: Sequential Organ Failure Assessment Score. SIRS: systemic inflammatory response syndrome.