The Role of Mean Platelet Volume as a Predictor of Mortality in Critically Ill Patients: A Systematic Review and Meta-Analysis

Table 1

Characteristics of the study.

Authors

Year

Country

Study design

Setting

Nonsurvivors

Survivors

Number

Age (year)

Male (%)

MPV (fL)

APACHE II

SOFA

Number

Age (year)

Male (%)

MPV (fL)

APACHE II

SOFA

Becchi et al. [18]

2006

Italy

Prospective

Sepsis

44

NA

NA

10.0 ± 1.7

NA

NA

26

NA

NA

10.5 ± 0.9

NA

NA

Kucukardali et al. [17]

2010

Turkey

Retrospective

All

62

76.5 ± 11.1

NA

8.5 ± 1.5

17.7 ± 5.0

NA

68

65.7 ± 21.6

NA

8.3 ± 1.2

13.59 ± 5.81

NA

Guclu et al. [19]

2013

Turkey

Retrospective

Sepsis

94

60.7 ± 18.5

55 (58.5)

7.0 (7.0, 9.0)

NA

NA

51

66.5 ± 18.5

29 (56.9)

8.0 (7.0, 9.0)

NA

NA

Kitazawa et al. [20]

2013

Japan

Retrospective

Sepsis

25

72.3 ± 11.3

17 (68.0)

7.5 ± 1.1

NA

NA

325

66.8 ± 15.7

168 (52.0)

7.6 ± 1.0

NA

NA

Sadaka et al. [21]

2014

USA

Retrospective

Sepsis

170

70.0 ± 14.0

NA

10.6 ± 0.9

27 ± 9.0

11.3 ± 2.9

314

66 ± 15

NA

10.5 ± 0.9

23.0 ± 7.0

9.8 ± 2.8

Zampieri et al. [24]

2014

Brazil

Prospective

All

24

50.4 ± 19.5

14 (58.0)

10.8 (10.1, 11.2)

NA

8.4 ± 4.6

60

50.3 ± 16.4

31 (52.0)

10.9 (10.2, 11.7)

NA

4.3 ± 3.7

Sezgi et al. [23]

2015

Turkey

Retrospective

All

95

69.0 ± 14.3

60 (73.2)

8.8 ± 2.3

28.1 ± 9.6

NA

80

62.4 ± 15.2

36 (45.0)

9.1 ± 2.4

21.1 ± 8.8

NA

Zhang et al. (Z) [25]

2014

China

Retrospective

All

443

63.1 ± 20.0

307 (69.3)

11.1 ± 1.4

NA

NA

1113

60.7 ± 19.0

714 (64.1)

10.5 ± 1.4

NA

NA

Gao et al. [22]

2014

China

Retrospective

Sepsis

88

61.7 ± 17.9

NA

11.2 (10.5, 12.5)

35 (27, 37.5)

NA

36

61.2 ± 20.6

NA

10.3 (9.7, 11.0)

30 (28, 33)

NA

Kim et al. [26]

2015

Korea

Prospective

Sepsis

35

68.9 ± 13.0

25 (71.0)

9.5 ± 1.7

25.9 ± 6.8

11.1 ± 3.0

310

63.7 ± 15.9

144 (46.5)

8.5 ± 1.1

16.5 ± 6.6

7.7 ± 2.6

Zhang et al. (S) [27]

2015

China

Retrospective

All

57

64 (53, 76)

35 (61.4)

15.8 ± 4.3

18 (13, 25.5)

9 (7, 14)

204

52 (43, 61)

156 (76.5)

12.8 ± 8.5

11 (8, 16)

5 (3, 8)

Note. The data presented are age, MPV, APACHE II, and SOFA shown as mean ± SD, median (IQR), and (%); NA: not available; Number: number of patients in the study; MPV: mean platelet volume; fL: femtoliter; APACHE II: acute physiologic and chronic health evaluation II score; SOFA: sepsis and organ failure assessment score. All the data are a mix of all the ICU population.