Research Article
Plasma KL-6 as a Potential Biomarker for Bronchopulmonary Dysplasia in Preterm Infants
Table 1
Perinatal characteristics of the patients.
| Characteristics | No/mild BPD (n = 48) | Moderate/severe BPD (n = 47) | value | Mean | SD | Mean | SD |
| Weight (g) | 935.52 | 160.36 | 800.64 | 161.89 | <0.001 | GA (wks) | 26.58 | 0.77 | 26.00 | 0.91 | <0.001 | Mechanical ventilation (d) | 12.96 | 8.84 | 34.43 | 22.34 | <0.001 | O2 therapy (d) | 34.00 | 17.65 | 54.33 | 21.74 | <0.001 | Hospital stay (d) | 64.60 | 14.63 | 90.55 | 26.82 | <0.001 | CPAP, NIV (d) | 10.31 | 5.14 | 15.42 | 8.91 | 0.048 |
| | n | % | n | % | |
| Percentage <26 + 0 wks GA | 15 | 27.1 | 29 | 57.2 | 0.077 | C-section | 33 | 68.8 | 34 | 72.3 | 0.823 | Antenatal steroids | 42 | 87.5 | 33 | 70.2 | 0.047 | Maternal hypertension | 8 | 16.7 | 8 | 17.0 | 1.000 | Chorioamnionitis, pPROM | 28 | 58.3 | 24 | 51.1 | 0.539 | Apgar score <3 at 1 min | 13 | 27.1 | 16 | 34.0 | 0.509 | RDS III-IV gr | 42 | 87.5 | 46 | 97.9 | 0.111 | Surfactant applied | 48 | 100.0 | 47 | 100.0 | NA | PDA, lung hemorrhage | 2 | 4.2 | 13 | 27.7 | 0.002 | Sepsis | 6 | 12.5 | 11 | 23.4 | 0.190 | NEC | 1 | 2.1 | 6 | 12.8 | 0.059 | ROP | 19 | 39.6 | 37 | 82.2 | <0.001 |
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SD, standard deviation; GA, gestational age; NIV, noninvasive ventilation, pPROM, preterm premature rupture of membranes; PDA, persistent ductus arteriosus; RDS, respiratory distress syndrome; NEC, necrotizing enterocolitis; ROP, retinopathy of prematurity.
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