Goal-directed therapy (GDT) is a cornerstone in the perioperative patient care and treatment of critically ill patients suffering from various diseases. Based on adequate monitoring techniques, goal-directed algorithms can facilitate early detection of pathophysiological changes and influence therapies that may improve the clinical outcomes. However, there are still many controversies regarding the approaches for GDT in different categories of patients. Thus, the search for critical illnesses and conditions that might become candidates for GDT may be of significant importance.

We invite authors to submit original research and review articles elucidating the front of research and defining optimal targets for perioperative management and pre- and intrahospital treatment of critical conditions, subsequently describing goal-oriented therapeutical interventions. We are primarily interested in articles that explore aspects of goal-directed therapy in different clinical settings, but we also invite researchers to present animal models of conditions that can potentially benefit from GDT. Potential topics include, but are not limited to:

• Perioperative goal-directed therapy: pro and contra
• Hemodynamic optimization
• Goal-oriented respiratory management for critically ill patients
• Targets for therapy during anesthesia in cardiac and noncardiac surgery
• Prehospital critical illness chain of survival

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ccrp/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable: