Research Article

Aflatoxin-Related Immune Dysfunction in Health and in Human Immunodeficiency Virus Disease

Table 1

Demographic and clinical characteristics of HIV positive and HIV negative study participants.

CharacteristicHIV positiveHIV negative
High AF-ALBLow AF-ALBHigh AF-ALBLow AF-ALB

Total number of participants58584040

Age (mean ± SD years)38.28 9.6538.22 9.3039.50 18.2542.08 16.86

Gender number (%)
Male24 (41.4)17 (29.3)23 (57.5)22 (55)
Female34 (58.6)41 (70.7)17 (42.5)18 (45)

Viral load (mean ± SD copies/ml)85049±23069670260±19316300
CD4 count (mean ± SD cells/ L)316±266298±2301001±2091197±614

CDC classification number (%)
A10 (17.3)7 (12.1)
B25 (43.1)27 (46.5)
C23 (39.7)24 (41.4)

AF-ALB (mean ± SD pmol/mg albumin)1.44 0.560.59 0.241.31 0.360.70 0.14

Aflatoxin B1 albumin adducts (AF-ALB)—Mean ± SD =  pmoL/mg albumin; median = 0.91 pmoL/mg albumin; range = 0–3.48 pmoL/mg albumin.
“High AF-ALB” participants were 0.91 pmoL/mg albumin; “low AF-ALB” participants were 0.91 pmoL/mg albumin.
SD = standard deviation.