A Functional Polymorphism in B and T Lymphocyte Attenuator Is Associated with Susceptibility to Rheumatoid Arthritis

Table 1

Frequency of SNPs in BTLA gene in healthy Japanese donors.

Nucleotide no.	Exon	Original*	Mutant	Amino acid change	Frequency in Japanese
590	IV	A	C	Asn to Thr	15%
800	V	T	C	Leu to Pro	40%

SNPs in human BTLA gene were determined in healthy Japanese donors (𝑛=20) as described in Section 2.
*Nucleotide of human BTLA gene reported in NCBI database (DM004104 and NW_001838881.2).