Family History of Autoimmune Disease in Patients with Aicardi-Goutières Syndrome

Table 1

History of autoimmune disease in parents of cases and controls.

Characteristic	AGS cases	Control	OR	P value	95% CI
Maternal history of AI (yes/no)
No	26 (83.9%)	28 (90.3%)	1.00
Yes	5 (16.1%)	3 (9.7%)	1.75	0.453	0.39–8.27
Paternal history of AI (yes/no)
No	30 (96.8%)	31 (100.0%)	1.00
Yes	1 (3.2%)	0 (0.0%)	—	0.313^∗	—
Maternal and/or paternal history of AI (yes/no)
No	25 (80.7%)	28 (90.3%)	1.00
Yes	6 (19.4%)	3 (9.7%)	2.24	0.288	0.51–9.91

^∗𝑃 value from chi-squared test due to zero control subjects with a paternal history of AI.