Table 1: Comparison of software-based and visual positive/negative classification.

Visual evaluation   Collective A () Collective B () Total ()   Positive Negative Positive Negative Positive Negative EUROPattern              Positive 193 1 79 1 272 2  Negative 0 6 0 71 0 77 Concordance 99.5% 99.3% 99.4% -value 0.921 0.987 0.984 Sensitivity 100% 100% 100% Specificity 85.7% 98.6% 97.5% PPV 99.5% 98.8% 99.3% NPV 100% 100% 100%

: kappa-value indicating interrater agreement, PPV: positive predictive value, NPV: negative predictive value.