Figure 2: Correlation of circulating Tfh cells frequency and autoantibody in RA patients. (a) Relationship between the frequency of circulating Tfh cells and the positive anti-CCP antibody (, ) (). (b) Relationship between the frequency of circulating Tfh cells and the negative anti-CCP antibody (,) (). (c) Relationship between the frequency of circulating Tfh cells and the level of RF (, ) (). (d) Increased frequency of circulating Tfh cells in RA patients according to anti-CCP antibody. Horizontal lines show the median.