Treatment with CB2 Agonist JWH-133 Reduces Histological Features Associated with Erectile Dysfunction in Hypercholesterolemic Mice
Figure 5
JWH-133 protects ApoE−/− mouse corpus cavernosum against fibrosis. Collagen content was evaluated by sirius red staining in penis from wild type and ApoE−/− mice treated or not with JWH-133. (a) Quantification of collagen content into the corpus cavernosum. ((b)–(d)) Representative photomicrographs of penis sections showing the corpus cavernosum of wild type mice (b) and untreated (c) and treated (d) ApoE−/− mice. * (one-way ANOVA followed by the Bonferroni post-test). Each column represents the mean ± SEM () of smooth muscle cell/collagen content ratio in arbitrary unity (A.U.).
