Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune Systems

<table>Regulatory network between the bone and immune system: the figure shows the network architecture of regulatory interactions that maintain homeostasis of the skeletal systems. Osteoclast-induced FoxP3<sup>+</sup> CD8 T cells are capable of regulating the skeletal and the immune systems. </table>

Journal of Immunology Research

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Figure 3

Figure 3: Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune Systems 