Persistent Suppression of Type 1 Diabetes by a Multicomponent Vaccine Containing a Cholera Toxin B Subunit-Autoantigen Fusion Protein and Complete Freund’s Adjuvant

Table 1

NOD mouse treatment groups for rVV-mediated suppression of hyperglycemia.

Groups	Treatment (i.p. and s.c. inoculation)	PFU (rVV)	Age at injection
1 (𝑛=10)	PBS (naive)	0	5 and 7 wks
2 (𝑛=10)	CFA (1 : 0)	0	5 and 7 wks
3 (𝑛=10)	CFA (1 : 10)	0	5 and 7 wks
4 (𝑛=10)	CFA (1 : 100)	0	5 and 7 wks
5 (𝑛=10)	rVV-CTB::GAD + CFA (1 : 0)	2 × (5 × 10^7)	5 and 7 wks
6 (𝑛=10)	rVV-CTB::GAD + CFA (1 : 10)	2 × (5 × 10^7)	5 and 7 wks
7 (𝑛=10)	rVV-CTB::GAD + CFA (1 : 100)	2 × (5 × 10^7)	5 and 7 wks
8 (𝑛=10)	rVV-CTB::GAD	2 × (5 × 10^7)	5 and 7 wks