Current Gerontology and Geriatrics Research
Volume 2010 (2010), Article ID 927503, 5 pages
doi:10.1155/2010/927503
Case Report

Acquired Haemophilia A in the Elderly: Case Reports

Antonella Tufano, Antonio Coppola, Anna Guida, Ernesto Cimino, Angela Maria De Gregorio, Anna Maria Cerbone, and Giovanni Di Minno

Regional Reference Centre for Coagulation Disorders, Department of Clinical and Experimental Medicine, “Federico II” University Hospital, 80131 Naples, Italy

Received 1 July 2009; Revised 24 January 2010; Accepted 25 January 2010

Academic Editor: Moisés Bauer

Copyright © 2010 Antonella Tufano et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. P. Collins, N. Macartney, R. Davies, et al., “A population based, unselected, consecutive cohort of patie with acquired haemophilia A,” British Journal of Haematology, vol. 124, no. 1, pp. 86–90, 2004. View at Publisher · View at Google Scholar · View at Scopus
  2. P. W. Collins, S. Hirsch, T. P. Baglin, et al., “Acquired hemophilia A in the United Kingdom: a 2-year national surveillance study by the United Kingdom Haemophilia Centre Doctors' organisation,” Blood, vol. 109, no. 5, pp. 1870–1877, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  3. F. Baudo, H. Levesque, A. Huth-Kuhne, et al., “The European Acquired Haemophilia Registry (EACH2): a preliminary data analysis,” Haemophilia, vol. 14, supplement 2, p. 1, 2008.
  4. P. Collins, U. Budde, J. H. Rand, et al., “Epidemiology and general guidelines of the management of acquired haemophilia and von Willebrand syndrome,” Haemophilia, vol. 14, supplement 3, pp. 49–55, 2008.
  5. A. Huth-Kuhne, F. Baudo, P. Collins, et al., “International recommendations on the diagnosis and treatment of patients with Acquired hemophilia A,” Haematologica, vol. 94, no. 4, pp. 566–575, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  6. J. Delgado, V. Jimenez-Yuste, F. Hernandez-Navarro, and A. Villar, “Acquired haemophilia: review and meta-analysis focused on therapy and prognostic factors,” British Journal of Haematology, vol. 121, no. 1, pp. 21–35, 2003. View at Publisher · View at Google Scholar · View at Scopus
  7. S. Woods and B. Varghese, “Acquired hemophilia A presenting in an elderly man,” Canadian Medical Association Journal, vol. 177, no. 4, pp. 341–342, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  8. M. Shurafa, S. Raman, and I. Wollner, “Disappearance of factor VIII antibody after removal of primary colon adenocarcinoma,” American Journal of Hematology, vol. 50, no. 2, pp. 149–150, 1995. View at Scopus
  9. T. S. Lossing, C. K. Kasper, and D. I. Feinstein, “Detection of FVIII inhibitors with the partial thromboplastin time,” Blood, vol. 49, pp. 793–797, 1977.
  10. A. Wiestner, H. J. Cho, A. S. Asch, et al., “Rituximab in the treatment of acquired factor VIII inhibitors,” Blood, vol. 100, no. 9, pp. 3426–3428, 2002. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  11. S. Kain, T. S. Copeland, and M. F. Leahy, “Treatment of refractory autoimmune (acquired) haemophilia with anti-CD20 (rituximab),” British Journal of Haematology, vol. 119, no. 2, p. 578, 2002. View at Publisher · View at Google Scholar · View at Scopus
  12. M. Franchini, “Rituximab in the treatment of adult acquired hemophilia A: a systematic review,” Critical Reviews in Oncology/Hematology, vol. 63, no. 1, pp. 47–52, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  13. M. Franchini and G. Lippi, “Acquired factor VIII inhibitors,” Blood, vol. 112, no. 2, pp. 250–255, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  14. P. Machado, J. M. Raya, T. Martin, et al., “Successful response to rituximab in two cases of acquired haemophilia refractory to standard-therapy,” International Journal of Hematology, vol. 87, pp. 545–549, 2008.
  15. P. M. Mannucci, “Autoimmune haemophilia,” Blood Transfusion, vol. 6, pp. 6–7, 2008.
  16. O. F. Ballester, T. Wang, H. I. Saba, et al., “Classic hemophilia in elderly patients,” Journal of the American Geriatrics Society, vol. 40, no. 8, pp. 824–826, 1992. View at Scopus
  17. D. J. Meiklejohn and H. G. Watson, “Acquired haemophilia in association with organ-specific autoimmune disease,” Haemophilia, vol. 7, no. 5, pp. 523–525, 2001. View at Publisher · View at Google Scholar · View at Scopus