Gait and Equilibrium in Subcortical Vascular Dementia

Table 2

A synopsis of the drugs employed by the two groups of patients at baseline.

Drug utilization mg/day	Baseline	12 months	24 months	36 months
ACE inhibitors	54 patients	89 patients	94 patients	164 patients
Enalapril, mean (±SD) dose	27. 4 ± 4.3	25.56 ± 3.65	25.56 ± 3.65	25.56 ± 3.65
Ramipril, mean (±SD) dose	3.41 ± 2.8	3.1 ± 1.89	3.1 ± 1.89	3.1 ± 1.89
Quinapril, mean (±SD) dose	5.11 ± 1.1	7.41 ± 0.8	7.6 ± 1.4	9.41 ± 1.8
Sartan	78 patients	67 patients	89 patients	102 patients
Losartan, mean (±SD) dose,	45.56 ± 23.54	49.67 ± 21.23	49.67 ± 21.23	49.67 ± 21.23
Telmisartan, mean (±SD) dose	43.12 ± 12.23	45.12 ± 1.45	40.2 ± 9.7	41.3 ± 9.6
Candesartan, mean (±SD) dose	16. 2 ± 2.32	16. 7 ± 6.16	12. 2 ± 5.65	14. 2 ± 4.32
Calcium antagonists	84 patients	93 patients	123 patients	153 patients
Amlodipine, mean (±SD) dose	6.0 ± 4.10	5.6 ± 2.34	5.6 ± 2.34	5.6 ± 2.34
Felodipine, mean (±SD) dose	7.5 ± 2.21	6.9 ± 3.5	6.9 ± 3.5	6.9 ± 3.5
Lacidipine, means (±SD) dose	4.5 ± 1.34	7.5 ± 0.21	7.67 ±1.3	5.56 ± 2.7
Antidiabetic medication	86 patients	112 patients	98 patients	105 patients
Glimepiride, mean (±SD) dose	1.0 ± 0.34	1.5 ± 0.56	1.43 ± 0.87	2.5 ± 0.12
Glibenclamide, mean (±SD) dose	5.5 ± 2.12	6.7 ± 1.43	7.5 ± 2.12	7.7 ± 3.5
Repaglinide, mean (±SD) dose	2.5 ± 0.34	2.65 ± 1.34	3.0 ± 1.31	4.0 ± 0.3
Metformina, mean (±SD) dose	950.5 ± 43.30	1200.5 ± 140.3	950.7 ± 443.3	1150.5 ± 153.3
Antiplatelet drugs	111 patients	149 patients	210 patients	249 patients
Ticlopidine, mean (±SD) dose	250 mg, b.i.d	250 mg b.i.d	250 mg b.i.d	250 mg b.i.d
ASA	117 patients	224 patients	326 patients	378 patients
Mean (±SD) dose	300	300	300	300
Digoxin	23 patients	25 patients	25 patients	25 patients
Mean (±SD) dose	0.23 ± 0.12	0.22 ± 0.13	0.22 ± 0.13	0.22 ± 0.13
Loop diuretics	53 patients	87 patients	78 patients	96 patients
Furosemide	29.45 ± 7.89	28.56 ± 8.92	28.56 ± 8.92	28.56 ± 8.92
Thiazide diuretics	65 patients	87 patients	93 patients	114 patients
Amiloride or hydrocnlorothiazide, mean (±SD)	14.7 ± 7.50	17.7 ± 3.50	17.7 ± 3.50	17.7 ± 3.50
Lipid lowering drugs	87 patients	124 patients	84 patients	84 patients
Torvastatin mean (±SD) dose	20.34 ± 8.76	21.34 ± 6.76	21.34 ± 6.76	21.34 ± 6.76
Simvastatin mean (±SD) dose	21.34 ± 7.67	22.43 ± 7.21	22.43 ± 7.21	22.43 ± 7.21
Pravastatin mean (±SD) dose	19.87 ± 8.67	24.54 ± 8.12	24.54 ± 8.12	24.54 ± 8.12
Nitroglycerine or analogue	126 patients	119 patients	139 patients	149 patients
Isosorbide mononitrate, mean (±SD) dose	36.67 ± 11.2	35.34 ± 10.56	35.34 ± 10.56	35.34 ± 10.56
Bronchodilators	59 patients	87 patients	97 patients	104 patients
Steroids, mean (±SD) dose	25.78± 11.2	31.8± 7.7	21.8± 6.5	31.8± 7.3
A combination of the above therapies	112 patients	183 patients	245 patients	345 patients