A Quantitative Assessment of Tremor and Ataxia in Female FMR1 Premutation Carriers Using CATSYS

Figure 2

(a) Proportion of variation explained by each principal component based on all 24 CATSYS measures, and adjusted for age. The first 3 principal components account for the majority total data variation (~60%). (b) The 24 individual variables of the CATSYS and their correlation to the first 3 principal components. The first PC (PC1) summarizes predominantly all sway tasks; the second PC (PC2) is primarily correlated with intention tremor (DotTrem) and writing tremor (WritTrem) in both hands; the third PC (PC3) captures association with postural tremor (TremInt) and reaction time in both hands. S1: SwayO60_Mean, S2: SwayO60_Area, S3: SwayO60_Int, S4: SwayO30_Mean, S5: SwayO30_Area, S6: SwayO30_Int, S7: SwayC30_Mean, S8: SwayC30_Area, S9: SwayC30_Int, S10: SwayC10_Mean, S11: SwayC10_Area, S12: SwayC10_Int, T1: TremInt_Dom, T2: TremIntNon_Dom, D1: DotTremInt_Dom, D2: DotTremIntNon_Dom, W1: WritTremInt_Dom, W2: WritTremIntNon_Dom, M1: Maxfreq_Dom, M2: MaxfreqNon_Dom, M3: MaxfreqTap_Dom, M4: MaxfreqTapNon_Dom, R1: ReactAvg_Dom, R2: ReactAvgNon_Dom.

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