A Quantitative Assessment of Tremor and Ataxia in Female FMR1 Premutation Carriers Using CATSYS
Table 2
Comparison of a priori primary outcome CATSYS measures.
Control ()
Non-FXTAS ()
FXTAS ()
CATSYS group
CATSYS performance task
Mean
SD
Mean
SD
Mean
SD
FXTAS versus control
Non-FXTAS versus control
FXTAS versus non-FXTAS
Postural Tremor, Tremor intensity (m/sec2)
Hand:
Dominant
0.11
0.04
0.10
0.05
0.69
1.42
***
nsa
***
Nondominant
0.10
0.04
0.09
0.04
0.98
2.51
***
ns
***
Intention Tremor, Tremor intensity (m/sec2)
Hand:
Dominant
2.24
1.47
2.14
1.31
2.33
2.50
ns
ns
ns
Nondominant
2.09
1.07
2.20
1.10
2.54
2.21
ns
ns
ns
Postural sway area (mm2)
60 Sec:
Eyes open
7.94
4.29
11.21
9.99
41.95
35.04
***
0.0756
***
30 Sec:
Eyes open
5.17
3.24
7.97
9.78
25.41
22.25
***
ns
***
Eyes closed
8.86
6.57
14.42
13.33
48.32
46.59
***
0.0295
***
10 Sec:
Eyes closed
5.77
3.61
11.00
16.27
46.81
55.49
***
ns
***
Analysis based on logarithm transformed data and adjusted for age.
aNot significant ().
***
(significant after P value adjustment for multiple testing).
