Age-Related Changes in the Hepatic Pharmacology and Toxicology of Paracetamol

Figure 2

Age-related pseudocapillarisation of the liver sinusoid impairs the transfer of lipids (chylomicrons remnants) and paracetamol across the fenestrated liver sinusoidal endothelial cells (LSECs). Adapted from Le Couteur et al., 2002 (20).