- About this Journal ·
- Abstracting and Indexing ·
- Aims and Scope ·
- Article Processing Charges ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Recently Accepted Articles ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
Current Gerontology and Geriatrics Research
Volume 2011 (2011), Article ID 791765, 6 pages
Does the Serum Testosterone Level Have a Relation to Coronary Artery Disease in Elderly Men?
1Department of Internal Medicine, Specialized Medical Hospital, Faculty of Medicine, Mansoura University, B.O. Pox 35516,
Al-Gomhoria Street, Mansoura, Egypt
2Department of Cardiology, Faculty of Medicine, Mansoura University, B.O. Pox 35516, Mansoura, Egypt
3Department of Clinical Pathology, Faculty of Medicine, Mansoura University, B.O. Pox 35516, Mansoura, Egypt
Received 4 January 2011; Revised 12 March 2011; Accepted 19 March 2011
Academic Editor: Fulvio Lauretani
Copyright © 2011 Mohamed A. Helaly et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- S. K. Glen and N. A. Boon, “Coronary artery disease in the elderly,” Reviews in Clinical Gerontology, vol. 9, no. 1, pp. 13–21, 1999.
- G. B. Phillips, B. H. Pinkernell, and T. Y. Jing, “The association of hypotestosteronemia with coronary artery disease in men,” Arteriosclerosis and Thrombosis, vol. 14, no. 5, pp. 701–706, 1994.
- G. M. C. Rosano, I. Sheiban, R. Massaro et al., “Low testosterone levels are associated with coronary artery disease in male patients with angina,” International Journal of Impotence Research, vol. 19, no. 2, pp. 176–182, 2007.
- B. B. Yeap, Z. Hyde, O. P. Almeida et al., “Lower testosterone levels predict incident stroke and transient ischemic attack in older men,” Journal of Clinical Endocrinology and Metabolism, vol. 94, no. 7, pp. 2353–2359, 2009.
- E. Braunwald, “Unstable angina. A classification,” Circulation, vol. 80, no. 2, pp. 410–414, 1989.
- S. Savonitto, D. Ardissino, C. B. Granger et al., “Prognostic value of the admission electrocardiogram in acute coronary syndromes,” Journal of the American Medical Association, vol. 281, no. 8, pp. 707–713, 1999.
- S. D. Paul, P. T. O'Gara, Z. A. Mahjoub, et al., “Geriatric patients with acute myocardial infarction: cardiac risk factor profiles, presentation, thrombolysis, coronary interventions, and prognosis,” American Heart Journal, vol. 131, no. 4, pp. 710–715, 1996.
- J. Dyas, G. F. Read, and D. Riad-Fahmy, “A simple robust assay for testosterone in male plasma using an -radioligand and a solid-phase separation technique,” Annals of Clinical Biochemistry, vol. 16, no. 6, pp. 325–331, 1979.
- D. Riad-Fahmy, G. F. Read, S. J. Gaskell, J. Dyas, and R. Hindawi, “A simple, direct radioimmunoassay for plasma cortisol, featuring a radioligand and a solid-phase separation technique,” Clinical Chemistry, vol. 25, no. 5, pp. 665–668, 1979.
- E. K. O. Kruithof, G. Nicolosa, and F. Bachmann, “Plasminogen activator inhibitor 1: development of a radioimmunoassay and observations on its plasma concentration during venous occlusion and after platelet aggregation,” Blood, vol. 70, no. 5, pp. 1645–1653, 1987.
- M. Alessi, M. Ailloud, and I. Juttor-Vague, “Features of risk thrombosis and atherosclerosis,” Feul Biology, vol. 179, pp. 39–41, 1994.
- K. T. Khaw, M. Dowsett, E. Folkerd et al., “Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: european prospective investigation into cancer in Norfolk (EPIC-Norfolk) prospective population study,” Circulation, vol. 116, no. 23, pp. 2694–2701, 2007.
- P. Y. Liu, A. K. Death, and D. J. Handelsman, “Androgens and cardiovascular disease,” Endocrine Reviews, vol. 24, no. 3, pp. 313–340, 2003.
- G. A. Laughlin, E. Barrett-Connor, and J. Bergstrom, “Low serum testosterone and mortality in older men,” Journal of Clinical Endocrinology and Metabolism, vol. 93, no. 1, pp. 68–75, 2008.
- S. M. Haffner, L. Mykkanen, R. A. Valdez, and M. S. Katz, “Relationship of sex hormones to lipids and lipoproteins in nondiabetic men,” Journal of Clinical Endocrinology and Metabolism, vol. 77, no. 6, pp. 1610–1615, 1993.
- D. Simon, M. A. Charles, K. Nahoul et al., “Association between plasma total testosterone and cardiovascular risk factors in healthy adult men: the telecom study,” Journal of Clinical Endocrinology and Metabolism, vol. 82, no. 2, pp. 682–685, 1997.
- W. Barud, R. Palusinski, J. Beltkowski, and G. Wojcicka, “Inverse relationship between total testosterone and anti-oxidized low density lipoprotein levels in aging males,” Atherosclerosis, vol. 164, no. 2, pp. 282–288, 2002.
- J. M. Zmuda, J. A. Cauley, A. Kriska, N. W. Glynn, J. P. Gutai, and L. H. Kuller, “Longitudinal relation between endogenous testosterone and cardiovascular disease risk factors in middle-aged men: a 13-year follow-up of former multiple risk factor intervention trial participants,” American Journal of Epidemiology, vol. 146, no. 8, pp. 609–617, 1997.
- K. T. Khaw and E. Barrett-Connor, “Blood pressure and endogenous testosterone in men: an inverse relationship,” Journal of Hypertension, vol. 6, no. 4, pp. 329–332, 1988.
- S. Dobrzycki, W. Serwatka, S. Nadlewski, et al., “An assessment of correlations between endogenous sex hormones levels and the extensiveness of coronary heart disease and the ejection fraction of the left ventricle in males,” Journal of Medical Investigation, vol. 50, pp. 162–169, 2003.
- G. D. Smith, Y. Ben-Shlomo, A. Beswick, J. Yarnell, S. Lightman, and P. Elwood, “Cortisol, testosterone, and coronary heart disease: prospective evidence from the caerphilly study,” Circulation, vol. 112, no. 3, pp. 332–340, 2005.
- A. E. Hak, J. C. Witteman, F. H. de Jong, M. I. Geerlings, A. Hofman, and H. A. Pols, “Low levels of endogenous androgens increase the risk of atherosclerosis in elderly men: the Rotterdam study,” Journal of Clinical Endocrinology and Metabolism, vol. 87, no. 8, pp. 3632–3639, 2002.
- M. A. Yialamas, A. A. Dwyer, E. Hanley, H. Lee, N. Pitteloud, and F. J. Hayes, “Acute sex steroid withdrawal reduces insulin sensitivity in healthy men with idiopathic hypogonadotropic hypogonadism,” Journal of Clinical Endocrinology and Metabolism, vol. 92, no. 11, pp. 4254–4259, 2007.
- M. Maggio, S. Basaria, A. Ble et al., “Correlation between testosterone and the inflammatory marker soluble interleukin-6 receptor in older men,” Journal of Clinical Endocrinology and Metabolism, vol. 91, no. 1, pp. 345–347, 2006.
- C. J. Malkin, P. J. Pugh, R. D. Jones, D. Kapoor, K. S. Channer, and T. H. Jones, “The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men,” Journal of Clinical Endocrinology and Metabolism, vol. 89, no. 7, pp. 3313–3318, 2004.
- A. S. Dobs, P. S. Bachorik, S. Arver et al., “Interrelationships among lipoprotein levels, sex hormones, anthropometric parameters, and age in hypogonadal men treated for 1 year with a permeation-enhanced testosterone transdermal system,” Journal of Clinical Endocrinology and Metabolism, vol. 86, no. 3, pp. 1026–1033, 2001.