Sterol Lipid Metabolism in Down Syndrome Revisited: Down Syndrome Is Associated with a Selective Reduction in Serum Brassicasterol Levels

Figure 1

Serum brassicasterol levels are reduced in Down Syndrome (DS) subjects. Serum brassicasterol levels were quantified by GC-MS in 𝑁=20 DS and 𝑁=22 healthy controls (CON). (a) Mean and standard error of brassicasterol levels in the total CON and DS sample. (b) Mean and standard error of brassicasterol levels in the CON and DS subjects <45 and >45 years of age. (c) Mean and standard error of brassicasterol levels in male and female CON and DS subjects. Data were analysed by Students 𝑡-test. *represents 𝑃<0.05, **represents 𝑃<0.01, and ***represents 𝑃<0.001.

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