Review Article

Pain Management in the Elderly: An FDA Safe Use Initiative Expert Panel’s View on Preventable Harm Associated with NSAID Therapy

Table 1

Factors that affect prescribing methods in elderly patients.

General factors

(1) “One-size-fits-all” approach not applicable
 (a) All geriatric patients
(2) Physiology
 (a) Renal decline
 (b) Hepatic decline
 (c) Body muscle/fat composition change
(3) Perception of pain varies
(4) Cognitive impairment
 (a) Medication literacy decline
 (b) Confusion about what, when, and how much
  medication to take
(5) Comorbidities
 (a) Interactions with medications
 (b) Require multiple medications
(6) Polypharmacy
 (a) Confusion about what, when, and how much
  medication to take
 (b) Overdosing
 (c) Drug-drug interactions
(7) Age-related factors interactions with medication
 (a) Increased susceptibility
 (b) Atypical presentation
 (c) Delayed/lack of detection
(8) Evidence-based practices
 (a) Lack of a roadmap to optimally manage pain
(9) Multiplicity of providers and lack of team approach to
  managing health conditions in the elderly
 (a) Multiple physicians prescribing
 (b) Pharmacists
 (c) Self/consumer
 (d) Insurance companies
(10) Cost/coverage of medications