Oxidative Stress and Down Syndrome: A Route toward Alzheimer-Like Dementia

<table>Oxidative stress and down syndrome. Increased conditions of oxidative stress are caused by the overexpression of some of the genes encoded by Chr21. Among these, amyloid precursor protein (APP), copper-zinc superoxide dismutase (SOD1), and beta secretase (BACE2) can directly or indirectly lead to OS.</table>

Current Gerontology and Geriatrics Research

fig1

Figure 1

Figure 1: Oxidative Stress and Down Syndrome: A Route toward Alzheimer-Like Dementia 