Clinical Study

Clinical Predictors of Mortality in Adults with Intellectual Disabilities with and without Down Syndrome

Table 2

Summary of key variables entered into the survival model (categorical variables).

VariableVariable detailNon-DSDSTotal

DeceasedAs of July 20116627%4236.2%10830.0

DementiaCaregiver reported at baseline10.4%65.2%71.9

MedicationsAntipsychotic at baseline5823.8%3731.9%9526.4
Antipsychotic in any wave8334%4942.2%13236.7
Antidepressant at baseline3012.3%1714.7%4713.1
Antidepressant in any wave5623%2622.4%8222.8
Sedative-hypnotic at baseline52%65.2%113.1
Sedative-hypnotic in any wave249.8%1412.1%3810.6
Anxiolytic at baseline2510.2%119.5%3610.0
Anxiolytic in any wave5020.5%2622.4%7621.1
Anticonvulsant at baseline6627%3631%10228.3
Anticonvulsant in any wave8133.2%4841.4%12935.8

Seizure historySeizure history (current or past) at baseline8434.4%1412.1%9827.2
Seizures (actively) present at baseline3916%65.2%4512.5
Seizures reported in any of the four waves8032.8%4639.7%12635
New seizures reported after baseline166.6%1210.3%287.8

*Higher scores indicate greater deficits.
**Higher scores indicate greater yearly increase in deficits between 1995 and 2001.