Clinical Study

Clinical Predictors of Mortality in Adults with Intellectual Disabilities with and without Down Syndrome

Table 5

Multivariate Cox regression analysis of mortality, as of July 2011.

β (SE)Sig.Hazard ratio (95% CI)

Down Syndrome−0.34 (1.00)NS0.10–5.11
Sex (ref: male)−0.58 (0.23)<0.050.36–0.88
Baseline age0.06 (0.01)<0.00011.05–1.09
Baseline DMR practical skills deficits0.09 (0.03)<0.0051.03–1.16
Baseline Reiss behavioral depression0.25 (0.06)<0.00051.12–1.44
Baseline anticonvulsant use0.71 (0.33)<0.051.07–3.90
DMR Sum of Social Scores change per year0.27 (0.05)<0.00011.18–1.45
History of seizure at or before baseline0.50 (0.24)<0.051.04–2.63
Seizure before or during the study−0.69 (0.31)<0.050.28–0.91
Baseline age DS interaction0.04 (0.02)0.081.00–1.08