Comparative Evaluation of the Antidiabetic Effects of Different Parts of Cassia fistula Linn, a Southeast Asian Plant

Table 5

Effect of methanolic and aqueous bark, leaf, and flower extracts of Cassia fistula on serum Lipid profile in diabetic rats.

Group	TC (mg/dL)	TG (mg/dL)	HDL-C (mg/dL)	Non-HDL-C (mg/dL)
Normal control	59.96±1.84	81.23±4.15	32.2±1.4	27.7±3.04
Diabetic control	108.7±3.91	170.1±3.60	22.3±0.7	86.4±4.20
Glibenclamide (2.5 mg/kg)	67.74 ± 3.34^c	84.03 ± 2.20^c	29.9 ± 1.1^c	37.9 ± 3.07^c
BME 250 mg/kg	84.54 ± 6.47^c	131 ± 2.92^c	26.8±1.1	58.2 ± 6.22^c
BAE 250 mg/kg	96.16±2.60	158.6±2.94	24.9±0.5	71.3 ± 2.15^a
BME 500 mg/kg	74.32 ± 2.34^c	90.41 ± 3.07^c	28.3 ± 0.8^b	46 ± 2.35^c
BAE 500 mg/kg	90.24 ± 1.61^b	156.4 ± 3.19^a	25.8±1.4	64.5 ± 2.84^c
LME 250 mg/kg	94.45 ± 2.46^a	157.3 ± 1.81^a	24.7±1.1	69.8 ± 2.53^a
LAE 250 mg/kg	101.4±3.36	160.2±3.33	24.1±1.1	77.3±4.13
LME 500 mg/kg	78.25 ± 3.40^c	96.13 ± 2.51^c	27.2 ± 0.9^a	51 ± 3.50^c
LAE 500 mg/kg	98.74±3.11	159.2±2.3	25.2±1.6	73.5±2.23
FME 250 mg/kg	101.8±4.26	160 ± 3.34	24.4±1.2	77.3±5.05
FAE 250 mg/kg	103.5±2.59	161.9±1.90	23.6±0.6	80 ± 2.15
FME 500 mg/kg	97.29±3.36	153.9 ± 3.86^b	26.2±1.5	71 ± 3.74^a
FAE 500 mg/kg	100.5±3.77	160.4±2.99	24.9±1.3	75.6±3.29

Values are mean ± SEM (𝑛=6).
𝑃 value: ^a<0.05, ^b<0.01, ^c<0.001 as compared with diabetic control group (by one-way ANOVA followed by Dunnett’s multiple comparison test).