Comparative Evaluation of the Antidiabetic Effects of Different Parts of Cassia fistula Linn, a Southeast Asian Plant

Table 7

Effect of methanolic bark, leaf and, flower extract of Cassia fistula on glucose uptake by isolated rat hemidiaphragm in vitro assay on normal rats.

Group	Incubation medium	Glucose up take (mg/g per 30 min)
1	Tyrode solution with glucose (2000 mg/L) control group	4.83±0.32
2	Tyrode solution with glucose (2000 mg/L) + insulin (0.25 IU/mL)	8.73 ± 0.4^b
3	Tyrode solution with glucose (2000 mg/L) + bark methanolic extract of C. fistula (25 mg/mL)	6.15 ± 0.21^a
4	Tyrode solution with glucose (2000 mg/L) + insulin (0.25 IU/mL) + bark methanolic extract of C. fistula (25 mg/mL)	13.66 ± 0.21^b
5	Tyrode solution with glucose (2000 mg/L) + leaf methanolic extract of C. fistula (25 mg/mL)	5.64±0.33
6	Tyrode solution with glucose (2000 mg/L) + insulin (0.25 IU/mL) + leaf methanolic extract of C. fistula (25 mg/mL)	11.69 ± 0.42^b
7	Tyrode solution with glucose (2000 mg/L) + flower methanolic extract of C. fistula (25 mg/mL)	5.14±0.24
8	Tyrode solution with glucose (2000 mg/L) + insulin (0.25 IU/mL) + flower methanolic extract of C. fistula (25 mg/mL)	9.20 ± 0.13^b

Values are mean ± SEM (𝑛=4).
𝑃 values: ^a<0.01, ^b<0.001, as compared with control group (by one-way ANOVA followed by Dunnett’s multiple comparison test).