Research Article

Optimizing Liposomal Cisplatin Efficacy through Membrane Composition Manipulations

Figure 4

Accumulation of platinum in the spleen (a), liver (b), and kidneys (c) of BDF-1 mice (n = 3, Mean ± SD) following the injection of cisplatin at 3 mg/kg as free drug (■); liposomal cisplatin DSPC : DSPG : CHOL (7 : 2 : 1) (light-gray square), or liposomal cisplatin DSPC : DPPC : DSPG : CHOL (35 : 35; 20 : 10) (dark-gray square).
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(a)
213848.fig.004b
(b)
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