Development of an Oral Form of Azacytidine: Triacetyl-5-Azacytidine
Figure 3
Effect of DNMT inhibitors on global DNA methylation in tissues of mice exposed for 5 days to ACT or TAC. (a) Dot blot of mouse tissues isolated 24 hours after treatment with 25 mg/kg i.v. ACT or 38 mg/kg p.o. TAC. Groups were compared to untreated animals (unt). (b) Densitometry of methylation levels represented in (a).
