Review Article

Novel Drugs Targeting the Epidermal Growth Factor Receptor and Its Downstream Pathways in the Treatment of Colorectal Cancer: A Systematic Review

Figure 1

Schematic diagram showing various drugs acting on EGFR and its subsequent pathways. MEK: MAPK (mitogen-activated protein kinase) kinases/extracellular-signal-regulated kinases, ERK: extracellular-signal-related kinase; PTEN: phosphatase and tensin homolog, mTOR: mammalian target of rapamycin.
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