Neoadjuvant Chemoradiation in Squamous Cell Carcinoma of the Maxillary Sinus: A 26-Year Experience

Table 2

Univariate analysis of prognostic factors.

Variable	5-year OS	P value	5-year LRC	P value
All patients	35.0%		58.6%
Age		0.089		0.627
≤58 years (lower half of median)	43.9%		63.9%
>58 years (upper half of median)	26.9%		52.1%
Gender		0.178		0.951
Male	30.3%		60.1%
Female	50.0%		56.3%
cT-classification		0.497		0.135
T2	33.3%		100%
T3	30.3%		70.0%
T4a	39.1%		56.1%
T4b	20.0%		25.0%
cN-classification		0.834		0.235
N0	37.2%		64.0%
N1	53.3%		100%
N2	28.1%		45.3%
UICC stage grouping		0.228		0.191
II	50.0%		100%
III	22.5%		64.3%
IVa	39.7%		59.0%
IVb	20.0%		25.0%
Complete response (CR)		0.021		0.136
No	26.0%		52.0%
Yes	70.0%		78.8%
Orbital infiltration		0.005		<0.001
No	44.0%		23.3%
Yes	0%		68.2%
Radiotherapy		0.501		0.950
40 Gy	41.7%		58.9%
50 Gy	31.3%		57.8%
Chemotherapy		0.673		0.409
Carboplatin	31.7%		49.4%
Cisplatin	37.2%		63.9%