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Chemotherapy Research and Practice
Volume 2012 (2012), Article ID 549170, 5 pages
http://dx.doi.org/10.1155/2012/549170
Clinical Study

Induction Chemotherapy in Locally Advanced Pharyngolaryngeal Cancers with Stridor: Is It Feasible and Safe?

1Department of Medical Oncology, Tata Memorial Hospital, Mumbai 400012, India
2Department of Surgical Oncology, Tata Memorial Hospital, Mumbai 400012, India
3Department of Radio-Diagnosis, Tata Memorial Hospital, Mumbai 400012, India

Received 1 May 2012; Revised 5 July 2012; Accepted 6 July 2012

Academic Editor: Vassilios A. Georgoulias

Copyright © 2012 Vijay Maruti Patil et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. MacKenzie, E. Franssen, J. Balogh, D. Birt, and R. Gilbert, “The prognostic significance of tracheostomy in carcinoma of the larynx treated with radiotherapy and surgery for salvage,” International Journal of Radiation Oncology Biology Physics, vol. 41, no. 1, pp. 43–51, 1998. View at Publisher · View at Google Scholar · View at Scopus
  2. P. J. Bradley, “Treatment of the patient with upper airway obstruction caused by cancer of the larynx,” Otolaryngology, vol. 120, no. 5, pp. 737–741, 1999. View at Publisher · View at Google Scholar · View at Scopus
  3. D. Herchenhorn, F. L. Dias, C. G. Ferreira et al., “Impact of previous tracheotomy as a prognostic factor in patients with locally advanced squamous cell carcinoma of the larynx submitted to concomitant chemotherapy and radiation,” ORL Journal, vol. 70, no. 6, pp. 381–388, 2008. View at Publisher · View at Google Scholar · View at Scopus
  4. B. Mittal, J. E. Marks, and J. H. Ogura, “Transglottic carcinoma,” Cancer, vol. 53, no. 1, pp. 151–161, 1984. View at Scopus
  5. N. V. Chernov, A. L. Klochikhin, and G. I. Markov, “Tracheostomy in patients with locally advanced laryngeal cancer,” Vestnik Otorinolaringologii, no. 2, pp. 52–54, 2005. View at Scopus
  6. J. F. Carrillo, M. Frías-Mendívil, C. Lopez-Graniel, A. I. Beitia, and F. J. Ochoa-Carrillo, “The impact of preoperative tracheotomy on T3 transglottic carcinomas of the larynx,” European Archives of Oto-Rhino-Laryngology, vol. 256, no. 2, pp. 78–82, 1999. View at Publisher · View at Google Scholar · View at Scopus
  7. F. C. Holsinger, M. S. Kies, E. M. Diaz et al., “Durable long-term remission with chemotherapy alone for stage II to IV laryngeal cancer,” Journal of Clinical Oncology, vol. 27, no. 12, pp. 1976–1982, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. A. A. Forastiere and A. R. Shaha, “Chemotherapy alone for laryngeal preservation—is it possible?” Journal of Clinical Oncology, vol. 27, no. 12, pp. 1933–1934, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. J. K. Salama, K. M. Stenson, E. O. Kistner et al., “Induction chemotherapy and concurrent chemoradiotherapy for locoregionally advanced head and neck cancer: a multi-institutional phase II trial investigating three radiotherapy dose levels,” Annals of Oncology, vol. 19, no. 10, pp. 1787–1794, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. S. Urba, G. Wolf, A. Eisbruch et al., “Single-cycle induction chemotherapy selects patients with advanced laryngeal cancer for combined chemoradiation: a new treatment paradigm,” Journal of Clinical Oncology, vol. 24, no. 4, pp. 593–598, 2006. View at Publisher · View at Google Scholar · View at Scopus
  11. J. L. Lefebvre, D. Chevalier, B. Luboinski, A. Kirkpatrick, L. Collette, and T. Sahmoud, “Larynx preservation in pyriform sinus cancer: preliminary results of a European organization for research and treatment of cancer phase III trial,” Journal of the National Cancer Institute, vol. 88, no. 13, pp. 890–899, 1996. View at Publisher · View at Google Scholar · View at Scopus
  12. P. Y. Chu, T. L. Lee, and S. Y. Chang, “Impact and management of airway obstruction in patients with squamous cell carcinoma of the larynx,” Head and Neck, vol. 33, no. 1, pp. 98–102, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. G. J. Spector, D. G. Sessions, J. Lenox, D. Newland, J. Simpson, and B. H. Haughey, “Management of stage IV glottic carcinoma: therapeutic outcomes,” Laryngoscope, vol. 114, no. 8 I, pp. 1438–1446, 2004. View at Publisher · View at Google Scholar · View at Scopus
  14. J. J. Fagan and J. W. Loock, “Tracheostomy and peristomal recurrence,” Clinical Otolaryngology and Allied Sciences, vol. 21, no. 4, pp. 328–330, 1996. View at Scopus
  15. M. P. Kamath, M. C. Hegde, S. Sreedharan, K. Bhojwani, V. Vamadevan, and K. V. Vishwas, “Role of estimation of arterial blood gases in the management of stridor,” Indian Journal of Otolaryngology and Head and Neck Surgery, vol. 62, no. 2, pp. 125–130, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. J. B. Vermorken, E. Remenar, C. van Herpen et al., “Cisplatin, fluorouracil, and docetaxel in unresectable head and neck cancer,” The New England Journal of Medicine, vol. 357, no. 17, pp. 1695–1704, 2007. View at Publisher · View at Google Scholar · View at Scopus
  17. M. R. Posner, D. M. Hershock, C. R. Blajman et al., “Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer,” The New England Journal of Medicine, vol. 357, no. 17, pp. 1705–1715, 2007. View at Publisher · View at Google Scholar · View at Scopus
  18. R. Hitt, J. J. Grau, A. Lopez-Pousa, et al., “Final results of a randomized phase III trial comparing induction chemotherapy with cisplatin/5-FU or docetaxel/cisplatin/5-FU follow by chemoradiotherapy (CRT) versus CRT alone as first-line treatment of unresectable locally advanced head and neck cancer (LAHNC)2009,” Journal of Clinical Oncology, vol. 27, supplement 15, article 6009.
  19. G. H. Zalzal, “Stridor and airway compromise,” Pediatric Clinics of North America, vol. 36, no. 6, pp. 1389–1402, 1989. View at Scopus