Bone Loss after Allogeneic Haematopoietic Stem Cell Transplantation: A Pilot Study on the Use of Zoledronic Acid

Table 3

Metabolic parameters (mean values), 𝑛=36.

		Baseline	1 year	2 years
Serum	Calcium (mmol/L)	2.37±0.1	2.34±0.1	2.43±0.4
	Phosphate (mg/dL)	3.6±0.7	2.97±1.6	3.48±0.9
	Creatinine (mg/dL)	1.06±0.2	1.1±0.3	1.12±0.3
	Albumin (g/dL)	4.0±0.43	4.3±0.4	4.48±0.48
Urine	Ca (mmol/24 h)	5.15±2.3	3.3±0.8	3.44±3.0
	Dpd* (nmol/nmol creatinine)	6.2±4.6	3.6±3.2 *	3.2±1.4 **
Hormones^∘	Estradiol (pg/mL)	20.3±9.9	20.8±6.0	24.4±16.9
	FSH (IU/L)	43.9±25.6	70.9±46	43.7±33.0
	LH (lU/L)	21.3±16.2	31.6±22.3	21.9±18.5
Vitamin D3	OH (ng/mL)	10.4±6.2	17.8±11.7	26.7±11.2
	1,25 di-OH (pg/mL)	30.6±19.4	49.4±15.0	45.3±20.9

± SD: standard deviation; Dpd: deoxypyridinoline, *𝑃=0.009, **𝑃=0.044; °5/12 women had received hormone replacement therapy.