Preparation and In Vivo Evaluation of Dichloro(1,2-Diaminocyclohexane)platinum(II)-Loaded Core Cross-Linked Polymer Micelles

Figure 1

Scheme of the preparation of DACHPt/cl-micelles. DACHPt is first reacted with silver nitrate, forming the platinum complexes with much greater water solubility, followed by immobilization into cl-micelles by simple mixing in salt-free conditions.