Research Article

Healthcare Costs and Workloss Burden of Patients with Chemotherapy-Associated Peripheral Neuropathy in Breast, Ovarian, Head and Neck, and Nonsmall Cell Lung Cancer

Table 3

Three-month per-capita baseline resource use and healthcare costs of CAPN cases and non-CAPN controls.

(A) Main Sample: no diabetes(B) Diabetes Sample
CasesControls -valueaCasesControls -valuea

No.%No.%No.%No.%
4544547171

Resource use rate
Hospitalizations20445%19343%0.46924361%3346%0.1138
ED visits7517%6815%0.51392130%1623%0.3980
Outpatient visits44498%44598%0.818571100%7099%0.8185
Oncology18841%17438%0.34082637%3042%0.4795
Neurology225%112%0.048257%11%0.1025

Resource use amountMean(SD)Mean(SD) -valueaMean(SD)Mean(SD) -valuea

Hospitalizations1.96(5.53)1.48(3.21)0.09563.48(5.02)4.10(9.75)0.5702
ED visits0.24(0.70)0.21(0.58)0.35500.41(0.73)0.35(0.76)0.6310
Outpatient visits11.37(6.80)11.25(7.40)0.744912.80(6.08)11.28(6.76)0.1420
Oncology1.40(3.06)1.33(3.47)0.66731.38(3.10)1.44(2.97)0.9040
Neurology0.06(0.31)0.03(0.22)0.08480.07(0.26)0.01(0.12)0.1029

Total costs$17,797($22,255)$17,180($25,240)0.6698$22,308($24,970)$21,061($22,748)0.6898
 Drug costs$433($857)$467($1,148)0.6064$800($868)$646($824)0.2761
 Medical costs$17,363($22,185)$16,712($25,140)0.6527$21,508($24,871)$20,415($22,636)0.7268
  Inpatient$6,496($19,301)$5,928($21,811)0.6632$11,220($22,256)$9,382($21,412)0.4845
  ED$127($826)$102($576)0.6043$125($290)$122($340)0.9490
  Outpatient$10,336($10,186)$10,328($10,282)0.9900$9,725($8,672)$10,358($9,840)0.6935
   Oncology$438($1,329)$439($1,796)0.9841$379($996)$431($1,452)0.7989
   Neurology$10($61)$9($108)0.8812$24($163)$1($7)0.2435

CAPN indicates chemotherapy-associated peripheral neuropathy; SD, standard deviation; ED, emergency department.
a -values are determined using McNemar tests for proportions and paired -tests for continuous measures.