Healthcare Costs and Workloss Burden of Patients with Chemotherapy-Associated Peripheral Neuropathy in Breast, Ovarian, Head and Neck, and Nonsmall Cell Lung Cancer
Table 6
Per capita healthcare costs for CAPN cases and non-CAPN controls during the 12-month study period.
(A) Main Sample: no diabetes
(B) Diabetes Sample
Cases
Controls
-valuea
Cases
Controls
-valuea
mean
(SD)
mean
(SD)
mean
(SD)
mean
(SD)
454
454
71
71
Total healthcare costs
$69,950
($66,913)
$52,606
($55,554)
<.0001
$76,555
($63,379)
$54,816
($68,115)
0.0273
Chemotherapy costs
$16,984
($21,248)
$16,169
($27,055)
0.5744
$20,990
($31,501)
$13,033
($19,725)
0.0670
Drug costs
$3,744
($5,333)
$3,071
($4,927)
0.0419
$6,017
($7,461)
$4,223
($6,100)
0.1163
CAPN-related drugs
$595
($1,590)
$328
($1,041)
0.0016
$718
($1,401)
$371
($782)
0.0832
Medical costs
$49,223
($56,500)
$33,366
($36,931)
<.0001
$49,548
($46,428)
$37,561
($57,723)
0.1614
Inpatient
$14,050
($35,793)
$6,498
($15,558)
<.0001
$19,181
($38,190)
$15,148
($44,098)
0.5637
ED
$474
($1,093)
$263
($730)
0.0005
$798
($1,817)
$243
($535)
0.0172
Outpatient
$34,698
($36,712)
$26,606
($29,913)
<.0001
$29,569
($21,339)
$22,170
($29,244)
0.0921
Oncology
$5,469
($15,923)
$3,193
($8,478)
0.0072
$4,191
($6,950)
$2,344
($4,729)
0.0554
Neurology
$129
($319)
$46
($433)
0.0011
$326
($843)
$44
($278)
0.0103
Primary care
$7,772
($12,454)
$6,543
($9,920)
0.0979
$6,024
($7,341)
$4,472
($5,965)
0.1252
Other physician
$7,437
($13,782)
$6,804
($17,452)
0.5247
$6,235
($11,447)
$5,150
($16,025)
0.6502
Lab/pathology
$414
($1,825)
$289
($1,490)
0.2632
$485
($2,027)
$110
($193)
0.1237
Other outpatient
$13,476
($24,509)
$9,731
($18,345)
0.0064
$12,307
($16,297)
$10,049
($20,812)
0.4798
CAPN-related medical costs
$725
($2,005)
$491
($762)
CAPN indicates chemotherapy-associated peripheral neuropathy; SD, standard deviation; ED, emergency department.
a-values are determined using McNemar tests for proportions and paired -tests for continuous measures.