Research Article

Healthcare Costs and Workloss Burden of Patients with Chemotherapy-Associated Peripheral Neuropathy in Breast, Ovarian, Head and Neck, and Nonsmall Cell Lung Cancer

Table 6

Per capita healthcare costs for CAPN cases and non-CAPN controls during the 12-month study period.

(A) Main Sample: no diabetes(B) Diabetes Sample
CasesControls -valueaCasesControls -valuea

mean(SD)mean(SD)mean(SD)mean(SD)
4544547171

Total healthcare costs$69,950($66,913)$52,606($55,554)<.0001$76,555($63,379)$54,816($68,115)0.0273

Chemotherapy costs$16,984($21,248)$16,169($27,055)0.5744$20,990($31,501)$13,033($19,725)0.0670

Drug costs$3,744($5,333)$3,071($4,927)0.0419$6,017($7,461)$4,223($6,100)0.1163
 CAPN-related drugs$595($1,590)$328($1,041)0.0016$718($1,401)$371($782)0.0832

Medical costs$49,223($56,500)$33,366($36,931)<.0001$49,548($46,428)$37,561($57,723)0.1614
 Inpatient$14,050($35,793)$6,498($15,558)<.0001$19,181($38,190)$15,148($44,098)0.5637
 ED$474($1,093)$263($730)0.0005$798($1,817)$243($535)0.0172
 Outpatient$34,698($36,712)$26,606($29,913)<.0001$29,569($21,339)$22,170($29,244)0.0921
  Oncology$5,469($15,923)$3,193($8,478)0.0072$4,191($6,950)$2,344($4,729)0.0554
  Neurology$129($319)$46($433)0.0011$326($843)$44($278)0.0103
  Primary care$7,772($12,454)$6,543($9,920)0.0979$6,024($7,341)$4,472($5,965)0.1252
  Other physician$7,437($13,782)$6,804($17,452)0.5247$6,235($11,447)$5,150($16,025)0.6502
  Lab/pathology$414($1,825)$289($1,490)0.2632$485($2,027)$110($193)0.1237
  Other outpatient$13,476($24,509)$9,731($18,345)0.0064$12,307($16,297)$10,049($20,812)0.4798
 CAPN-related medical costs$725($2,005)$491($762)

CAPN indicates chemotherapy-associated peripheral neuropathy; SD, standard deviation; ED, emergency department.
a -values are determined using McNemar tests for proportions and paired -tests for continuous measures.