Lomustine Analogous Drug Structures for Intervention of Brain and Spinal Cord Tumors: The Benefit of In Silico Substructure Search and Analysis

Table 4

Path analysis causal effect on formula weight.

Property	Path coefficient
Log P	−0.085
Polar surface area	−0.027
Number of atoms	0.449
Number of oxygens and nitrogens	−0.027
Number of –OH and -NH𝑛	−0.026
Number of rotatable bonds	0.499
Molecular volume	0.005