Modulators of Protein Kinase C Affect SR-BI-Dependent HDL Lipid Uptake in Transfected HepG2 Cells
Figure 7
Modulators of PKC activity do not affect SR-BI distribution in HepG2 cells. HepG2[eGFP-SR-BI] cells were serum starved for 4 hrs and then refed medium containing 5% FBS and either vehicle (0.1% DMSO), 0.5 μM PMA, or 7.5 μM chelerythrine chloride and incubated for 1 hr. Cells were fixed with 2.5% paraformaldehyde and imaged by confocal microscopy.
