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Cholesterol
Volume 2012 (2012), Article ID 976578, 5 pages
http://dx.doi.org/10.1155/2012/976578
Clinical Study

Changes in Lipids and Lipoproteins after Selective LDL Apheresis (7-Year Experience)

11st Cardiology Department, Onassis Cardiac Surgery Center, 17674 Athens, Greece
2Internal Medicine Department, General Hospital “G. Papanikolaou”, Kimi, Greece
3Cardiology Department, Tzanio General Hospital, Piraeus, Greece

Received 30 September 2011; Revised 20 December 2011; Accepted 12 January 2012

Academic Editor: Peter J. Lansberg

Copyright © 2012 Genovefa Kolovou et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. A. Austin, C. M. Hutter, R. L. Zimmern, and S. E. Humpries, “Familial hypercholesterolemia and coronary heart disease: a HuGE association review,” American Journal of Epidemiology, vol. 160, no. 5, pp. 421–429, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  2. J. Emery, K. Barlow-Stewart, S. A. Metcalfe, and D. Sullivan, “Genetics and preventive health care,” Australian Family Physician, vol. 36, no. 10, pp. 808–811, 2007. View at Scopus
  3. A. K. Soutar and R. P. Naoumova, “Mechanisms of disease: genetic causes of familial hypercholesterolemia,” Nature Clinical Practice Cardiovascular Medicine, vol. 4, no. 4, pp. 214–225, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  4. M. Varret, M. Abifadel, J. P. Rabes, and C. Boileau, “Genetic heterogeneity of autosomal dominant hypercholesterolemia,” Clinical Genetics, vol. 73, no. 1, pp. 1–13, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  5. S. E. Leigh, A. H. Foster, R. A. Whittall, C. S. Hubbart, and S. E. Humphries, “Update and analysis of the university college london low density lipoprotein receptor familial hypercholesterolemia database,” Annals of Human Genetics, vol. 2, no. 4, pp. 485–498, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  6. J. H. Baumer and J. P. H. Shield, “Hypercholesterolaemia in children guidelines review,” Archives of Disease in Childhood. Education and Practice Edition, vol. 94, no. 3, pp. 84–86, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  7. D. Damgaard, M. L. Larsen, P. H. Nissen et al., “The relationship of molecular genetic to clinical diagnosis of familial hypercholesterolemia in a Danish population,” Atherosclerosis, vol. 180, no. 1, pp. 155–160, 2005. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  8. N. A. Neil, J. Cooper, D. J. Betteridge et al., “All-cause and cardiovascular mortality in treated patients with severe hypertriglyceridaemia: a long-term prospective registry study,” Atherosclerosis, vol. 211, no. 2, pp. 618–623, 2010. View at Publisher · View at Google Scholar · View at PubMed
  9. A. S. Wierzbicki, S. E. Humphries, and R. Minhas, “Familial hypercholesterolaemia: summary of nice guidance. Guideline development group,” British Medical Journal, vol. 337, article a1095, 2008. View at Publisher · View at Google Scholar
  10. W. T. Friedewald, R. I. Levy, and D. S. Fredrickson, “Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge,” Clinical Chemistry, vol. 18, no. 6, pp. 499–502, 1972. View at Scopus
  11. A. A. Kroon, M. A. Van't Hof, P. N. M. Demacker, and A. F. H. Stalenhoef, “The rebound of lipoproteins after LDL-apheresis. Kinetics and estimation of mean lipoprotein levels,” Atherosclerosis, vol. 152, no. 2, pp. 519–526, 2000. View at Publisher · View at Google Scholar · View at Scopus
  12. H. Scharnagl, M. Nauck, H. Wieland, and W. März, “The friedewald formula underestimates LDL cholesterol at low concentrations,” Clinical Chemistry and Laboratory Medicine, vol. 39, no. 5, pp. 426–431, 2001. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  13. A. A. Kroon, W. R. Aengevaeren, T. Van Der Werf et al., “LDL-apheresis atherosclerosis regression study (LAARS). Effect of aggressive versus conventional lipid lowering treatment on coronary atherosclerosis,” Circulation, vol. 93, no. 10, pp. 1826–1835, 1996. View at Scopus
  14. S. Nishimura, M. Sekiguchi, T. Kano et al., “Effects of intensive lipid lowering by low-density lipoprotein apheresis on regression of coronary atherosclerosis in patients with familial hypercholesterolemia: japan low-density lipoprotein apheresis coronary atherosclerosis prospective study (L-CAPS),” Atherosclerosis, vol. 144, no. 2, pp. 409–417, 1999. View at Publisher · View at Google Scholar · View at Scopus
  15. H. Mabuchi, J. Koizumi, M. Shimizu et al., “Long-term efficacy of low-density lipoprotein apheresis on coronary heart disease in familial hypercholesterolemia,” American Journal of Cardiology, vol. 82, no. 12, pp. 1489–1495, 1998. View at Publisher · View at Google Scholar
  16. G. Kolovou, D. Daskalova, I. Mastorakou, K. Anagnostopoulou, and D. V. Cokkinos, “Regression of achilles tendon xanthomas evaluated by CT scan after hypolipidemic treatment with simvastatin: a case report,” Angiology, vol. 55, no. 3, pp. 335–339, 2004. View at Publisher · View at Google Scholar · View at Scopus
  17. G. D. Kolovou, K. K. Anagnostopoulou, N. D. Pilatis et al., “Heterozygote men with familial hypercholesterolaemia may have an abnormal triglyceride response post-prandially. Evidence for another predictor of vascular risk in familial hypercholesterolaemia,” International Journal of Clinical Practice, vol. 59, no. 3, pp. 311–317, 2005. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  18. G. D. Kolovou, G. V. Dedoussis, K. K. Anagnostopoulou et al., “Management of a patient with a null low-density lipoprotein receptor mutation: a case report,” Angiology, vol. 57, no. 6, pp. 729–732, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  19. N. Masaki, R. Tatami, T. Kumamoto et al., “Ten-year follow-up of familial hypercholesterolemia patients after intensive cholesterol-lowering therapy,” International Heart Journal, vol. 46, no. 5, pp. 833–843, 2005. View at Publisher · View at Google Scholar · View at Scopus
  20. B. R. Gordon, S. F. Kelsey, P. C. Dau et al., “Long-term effects of low-density lipoprotein apheresis using an automated dextran sulfate cellulose adsorption system,” American Journal of Cardiology, vol. 81, no. 4, pp. 407–411, 1998. View at Publisher · View at Google Scholar · View at Scopus
  21. C. Keller, “LDL-apheresis in homozygous LDL-receptor-defective familial hypercholesterolemia: the Munich experience,” Atherosclerosis Supplements, vol. 10, no. 5, pp. 21–26, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. M. J. Koziolek, U. Hennig, A. Zapf et al., “Retrospective analysis of long-term lipid apheresis at a single center,” Therapeutic Apheresis and Dialysis, vol. 14, no. 2, pp. 143–152, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  23. V. Schettler, E. Wieland, V. W. Armstrong, T. Kleinoeder, R. W. Grunewald, and G. A. Müller, “First steps toward the establishment of a German low-density lipoprotein-apheresis registry: recommendations for the indication and for quality management,” Therapeutic Apheresis, vol. 6, no. 5, pp. 381–383, 2002. View at Publisher · View at Google Scholar
  24. Z. M. Szczepiorkowski, J. L. Winters, N. Bandarenko et al., “Guidelines on the use of therapeutic apheresis in clinical practice—evidence-based approach from the apheresis applications committee of the American society for apheresis,” Journal of Clinical Apheresis, vol. 25, no. 3, pp. 83–177, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  25. G. R. Thompson, “HEART-UK LDL apheresis working group. Recommendations for the use of LDL apheresis,” Atherosclerosis, vol. 198, no. 2, pp. 247–255, 2008. View at Publisher · View at Google Scholar · View at PubMed
  26. N. Koga and Y. Iwata, “Pathological and angiographic regression of coronary atherosclerosis by LDL-apheresis in a patient with familial hypercholesterolemia,” Atherosclerosis, vol. 90, no. 1, pp. 9–21, 1991. View at Scopus