Changes in Lipids and Lipoproteins after Selective LDL Apheresis (7-Year Experience)

Table 3

Lipid profile before and after LDL apheresis sessions in HFH and non-HFH patients.

	TC	TC HT corrected	TG	HDL cholesterol	LDL cholesterol
HFH
Preapheresis	344±81		93±36	37±8	288±81
Postapheresis	111±44	121±47	42±23	32±7	72±45
% difference	−68%±8%	−65%±9%	−55%±14%	−13%±7%	−76%±10%
Non-HFH
Preapheresis	284±79		541±885	45±14	196±39
Postapheresis	137±78	149±85	367±700	39±12	53±30
% difference	−53%±14%	−49%±15%	−42%±16%	−14%±8%	−72%±14%

All data were expressed as mg/dL, mean ± SD. The mean data were based on multiple measurements (𝑛=1216, only sessions which had at least three parameters, TC, TG, and HDL, measured were involved) during the total follow-up period. All values were significantly decreased 𝑃<0.001, except HDL cholesterol (𝑃=0.265) in non-HFH group. To convert cholesterol values (TC, HDL, and LDL) from mg/dL to mmol/l, multiply by 0.0259, and, for TGs, multiply by 0.0113. TG indicates triglycerides, and LDL indicates low-density lipoprotein, HDL indicates high-density lipoprotein (HT = hematocrit).