Table 1: Fasting metabolic parameters at 0 and 4 weeks after pitavastatin.

0 Weeks4 WeeksP

Body mass index (kg/m2)23.4 (21.3–29.2)23.7 (21.7–29.4)0.557
Total cholesterol (mg/dL) 0.0001
Low-density lipoprotein cholesterol (mg/dL) <0.0001
High-density lipoprotein cholesterol (mg/dL) 0.8321
Triglycerides (mg/dL)98.5 (78.0–138.8)89.5 (63.0–132.8)0.287
Remnant-like particle cholesterol (mg/dL) 0.1239
FFA (mEq/L) 0.8926
Apolipoprotein AI (mg/dL) 0.3207
Apolipoprotein B (mg/dL) 0.0004
Apolipoprotein E (mg/dL) 0.0735
Arachidonic acid ( g/mL) 0.0485
Eicosapentaenoic acid (μg/mL) 0.3319
Docosahexaenoic acid (μg/mL) 0.6055
Glucose (mg/dL) 0.4502
Insulin (μU/mL)5.9 (4.9–16.3)5.9 (2.8–15.7)0.028
HOMA-R1.28 (1.12–3.80)1.26 (0.56–3.47)0.322
High sensitivity CRP (mg/L) 0.187
Urinary 8OHdG (ng/mgCr) 0.1882
Urinary isoprostane (ng/mgCr) 0.4423
Urinary isoprostane production rate (ng/kg/hour) 0.4894
Serum creatinine (mg/dL) 0.8143
eGFR (mL/min/1.73 m2) 0.5168
Albumin/creatinine ratio (mg/gCr) 0.4383
(mL/minute) 0.0431
Serum uric acid (mg/dL) 0.4786
(mL/minute) 0.0072
/ (%) 0.0409
Uric acid excretion (mg/gCr) 0.2385
Adjusted urinary excretion of uric acid (mg/kg/hour) 0.0378

Values are shown as mean ± standard deviation. BMI, triglycerides, insulin, and HOMA-R are shown as median and interquartile range. HOMA-R: homeostasis model assessment ratio; 8OHdG: 8-Hydroxydeoxyguanosine; eGFR: estimated glomerular filtration rate; : creatinine clearance; : uric acid clearance.