Short-Term Effect of Pitavastatin Treatment on Glucose and Lipid Metabolism and Oxidative Stress in Fasting and Postprandial State Using a Test Meal in Japanese Men

Table 2

Changes in incremental area under the curve (iAUC) for each metabolic parameter after E460F18 loading at 0 and 4 weeks of pitavastatin treatment.

	0 week	4 week	P
Triglycerides (mg/dL)	3885 (2565–6480)	2745 (1883–4508)	0.007
Remnant-like particle cholesterol (mg/dL)	166±125	68±85	0.0012
Apolipoprotein E (mg/dL)	21±29	4±13	0.1333
Glucose (mg/dL)	882±2175	1491±2216	0.2289
Insulin	2342 (1202–3083)	2664 (1441–5439)	0.093
𝐶Cr (mL/minute)	5048±7975	6058±4660	0.7752
Albumin creatinine ratio	−68±194	−194±312	0.2424
𝐶UA (mL/minute)	536±317	534±292	0.9920
Adjusted urinary excretion of uric acid (mg/kg/hour)	−88±55	−37±53	0.0442

Values are shown as mean ± standard deviation. 𝐶_Cr: creatinine clearance; 𝐶_UA: uric acid clearance.
iAUC for triglycerides and insulin are shown as median and interquartile range.