HDL, Atherosclerosis, and Emerging Therapies

Table 1

Characteristics of pathways for cholesterol efflux from cells to plasma.

Characteristics	Aqueous diffusion	SR-BI	ABCA1	ABCG1
Energy requirement	Passive	Passive	Active	Active
Cholesterol flux	Bidirectional	Bidirectional	Unidirectional	Unidirectional
Preferred HDL acceptors	HDL2, HDL3	HDL2, HDL3	preβ-HDL; Lipid-poor/free apoA-I	HDL2, HDL3