Effects of Atorvastatin on Resting and Peak Exercise Blood Pressure among Normotensive Men and Women
Table 2
Average adjusted resting blood pressure change (mean ± SEM) after 6 mo of 80 mg atorvastatin or placebo among total sample and by drug and sex.
Resting BP (mmHg)
Total sample
Atorvastatin
Placebo
Pre
Pre
Pre
Total
SBP
118.9 ± 0.6
0.5 ± 0.5
115.3 ± 0.9
0.8 ± 0.7
114.7 ± 0.8
0.3 ± 0.6
DBP
75.3 ± 0.5
0.3 ± 0.5
75.5 ± 0.6
0.4 ± 0.7
75.2 ± 0.6
0.5 ± 0.6
MAP
87.7 ± 0.7
0.2 ± 0.8
88.5 ± 0.8
0.0 ± 0.8
86.8 ± 1.1
0.5 ± 1.3
Men
SBP
117.2 ± 0.8
1.2 ± 0.7
117.7 ± 1.2
2.7 ± 1.0
116.6 ± 1.1
−0.2 ± 1.0
DBP
76.5 ± 0.6
1.0 ± 0.7
75.0 ± 0.9
2.0 ± 1.0
77.0 ± 0.9
0.2 ± 0.9
MAP
89.3 ± 1.0
1.2 ± 1.0
90.1 ± 0.9
0.9 ± 1.2
87.7 ± 1.6
1.7 ± 1.8
Women
SBP
−0.1 ± 0.7
0.8 ± 0.8
DBP
−0.4 ± 0.7
0.8 ± 0.9
MAP
−0.7 ± 1.2
−0.7 ± 1.8
Adjusted for age, baseline BMI, baseline VO2peak, and sex. Pre, baseline; , after 6 months; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure. ; men versus women. ‡, atorvastatin versus placebo.
