Optimal Use of Plant Stanol Ester in the Management of Hypercholesterolemia

Figure 1

The full LDL-cholesterol-lowering effect of plant stanol ester can be detected after the daily consumption of 2 g/d plant stanols for 2 weeks. The effect is sustained as long as plant stanol ester is included in the daily diet; the longest intervention period in a clinical study has been 85 weeks. If the consumption is stopped, the plant stanol ester specific cholesterol-lowering effect will be lost within 1-2 weeks (modified from [18, 22, 24, 27, 32, 33, 35–37]).