Research Article
Evaluation of Antidiabetic and Antihyperlipidemic Effects of Peganum harmala Seeds in Diabetic Rats
Table 2
The mean values of fasting glucose and lipids (mg/dL) profile in serum of all groups (data shown as mean ± SD,
).
| Groups | FBG (mg/dL) | Triglyceride (mg/dL) | Total cholesterol (mg/dL) | HDL-c (mg/dL) | LDL-c (mg/dL) |
| Intact | 99.4 ± 17.8 | 67 ± 8.8 | 66.5 ± 6.7 | 31.3 ± 3.2 | 23.1 ± 4.8 | Control + 30 mg/kg extract | 85.9 ± 10 | 72.5 ± 18.9 | 68.8 ± 7.2 | 32.4 ± 4.1 | 22 ± 2.7 | Control + 60 mg/kg extract | 85.0 ± 18.0 | 50.8 ± 13.5 | 64 ± 12.4 | 31.5 ± 6.3 | 22.8 ± 7.3 | Control + 120 mg/kg extract | 99.6 ± 15.4 | 68.1 ± 20.1 | 67.4 ± 8 | 31.5 ± 4.2 | 22.4 ± 4.2 | Diabetic | 524.7 ± 75.6 | 91 ± 8.1 | 95.7 ± 4.2 | 25.6 ± 4.8 | 43.9 ± 12.8 | Diabetic + 30 mg/kg extract | 370.0 ± 111.7 | 82.2 ± 10.7 | 80.6 ± 9.7 | 35.1 ± 4.9 | 32.9 ± 6.8 | Diabetic + 60 mg/kg extract | 311.5 ± 59.5 | 70 ± 12.5 | 77.4 ± 14.4 | 34.5 ± 7.2 | 26.3 ± 6.6 | Diabetic + 120 mg/kg extract | 282.3 ± 45.3 | 69 ± 5.4 | 73 ± 6.2 | 45 ± 2.1 | 28.5 ± 3.1 |
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Statistically significant.
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