Evaluation of Antidiabetic and Antihyperlipidemic Effects of Peganum harmala Seeds in Diabetic Rats

Table 2

The mean values of fasting glucose and lipids (mg/dL) profile in serum of all groups (data shown as mean ± SD, ).

Groups	FBG (mg/dL)	Triglyceride (mg/dL)	Total cholesterol (mg/dL)	HDL-c (mg/dL)	LDL-c (mg/dL)
Intact	99.4 ± 17.8	67 ± 8.8	66.5 ± 6.7	31.3 ± 3.2	23.1 ± 4.8
Control + 30 mg/kg extract	85.9 ± 10	72.5 ± 18.9	68.8 ± 7.2	32.4 ± 4.1	22 ± 2.7
Control + 60 mg/kg extract	85.0 ± 18.0	50.8 ± 13.5	64 ± 12.4	31.5 ± 6.3	22.8 ± 7.3
Control + 120 mg/kg extract	99.6 ± 15.4	68.1 ± 20.1	67.4 ± 8	31.5 ± 4.2	22.4 ± 4.2
Diabetic	524.7 ± 75.6	91 ± 8.1	95.7 ± 4.2	25.6 ± 4.8	43.9 ± 12.8
Diabetic + 30 mg/kg extract	370.0 ± 111.7	82.2 ± 10.7	80.6 ± 9.7	35.1 ± 4.9	32.9 ± 6.8
Diabetic + 60 mg/kg extract	311.5 ± 59.5	70 ± 12.5	77.4 ± 14.4	34.5 ± 7.2	26.3 ± 6.6
Diabetic + 120 mg/kg extract	282.3 ± 45.3	69 ± 5.4	73 ± 6.2	45 ± 2.1	28.5 ± 3.1

Statistically significant.